Comparative Analysis of Cutaneous Fungi in Atopic Dermatitis Patients and Healthy Individuals
Yoojeong Choi, Kui Young Park, Hye Sung Han, Mi‐Kyung Lee, Seong Jun Seo
Abstract
Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease triggered by diverse factors. Microbes are one of the crucial risk factors for AD development or exacerbation. However, the effect of a fungal burden on AD has been overlooked compared to bacteria. Objective: This study aimed to comparatively analyze cutaneous fungal distribution between AD patients and healthy individuals by polymerase chain reaction (PCR)-based analysis. Methods: , were analyzed using specific primer and amplification methods. Amplicons were sequenced, and the fungal distribution of both groups were compared. Results: restricta was the most frequently identified species in the AD patient group, and the only species found in the healthy control group. Conclusion: spp. are altered with AD development.