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Chitosan-based buccal mucoadhesive bilayer tablets enhance the bioavailability of tizanidine hydrochloride by bypassing the first-pass metabolism

Muhammet Davut Arpa, Neslihan Üstündağ Okur, Mehmet Koray Gök, Erdal Cevher

2024Journal of Drug Delivery Science and Technology11 citationsDOI

Topics & Concepts

MucoadhesionChitosanBuccal administrationBioavailabilitySwellingNuclear chemistryChromatographyBilayerMaterials scienceEthyl celluloseHydrochlorideChemistryDrug deliveryDrug carrierPolymerPharmacologyOrganic chemistryBiochemistryMedicineComposite materialMembraneAdvanced Drug Delivery SystemsDrug Solubulity and Delivery SystemsAdvancements in Transdermal Drug Delivery
Chitosan-based buccal mucoadhesive bilayer tablets enhance the bioavailability of tizanidine hydrochloride by bypassing the first-pass metabolism | Litcius