Cesium carbonate-catalyzed synthesis of phosphorothioates <i>via S</i>-phosphination of thioketones
Ze-Wei Chen, Pratheepkumar Annamalai, Rekha Bai, Yongyi Hu, Satpal Singh Badsara, Kuo‐Wei Huang, Chin‐Fa Lee
Abstract
A highly efficient and environmentally-friendly base-mediated transition metal-free direct thiophilic catalytic approach is reported for the synthesis of S -benzhydryl-phosphorothioates by reacting phosphite nucleophiles with diarylmethanethione.
Topics & Concepts
CaesiumCatalysisCarbonateChemistryCombinatorial chemistryInorganic chemistryOrganic chemistrySulfur-Based Synthesis TechniquesSynthesis and Reactivity of Sulfur-Containing CompoundsChemical Synthesis and Reactions