Silk fibroin films with embedded magnetic nanoparticles: evaluation of the magneto-mechanical stimulation effect on osteogenic differentiation of stem cells
L. Del Bianco, Federico Spizzo, Yuejiao Yang, Gabriele Greco, Maria Laura Gatto, G. Barucca, Nicola M. Pugno, Antonella Motta
Abstract
By combining physical characterization data, in vitro biological tests and numerical calculations, we unveil the magneto-mechanical effect promoting the osteogenic differentiation of stem cells grown on silk fibroin films with magnetic nanoparticles.
Topics & Concepts
FibroinMaterials scienceNanoparticleMagnetic nanoparticlesNanotechnologyTissue engineeringSILKBiophysicsBiomedical engineeringComposite materialBiologyMedicineSilk-based biomaterials and applicationsBone Tissue Engineering MaterialsCellular Mechanics and Interactions