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Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes

Taylor Merfeld, Shuxia Peng, Bradley M. Keegan, Vincent M. Crowley, Christopher M. Brackett, Andrew Gutierrez, Nathan R. McCann, Tyelor S. Reynolds, Matthew C. Rhodes, Katherine M. Byrd, Junpeng Deng, Robert L. Matts, Brian S. J. Blagg

2023European Journal of Medicinal Chemistry17 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryGene isoformHsp90BiochemistryCytosolMitochondrionStructural similarityFunction (biology)Small moleculeTetramerCell biologyHeat shock proteinEnzymeGeneBiologyHeat shock proteins researchEnzyme Structure and FunctionATP Synthase and ATPases Research
Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes | Litcius