Recent discoveries on the structure of iodine(<scp>iii</scp>) reagents and their use in cross-nucleophile coupling
Adriano Bauer, Nuno Maulide
Abstract
This perspective article discusses structural features of iodine(<sc>iii</sc>) compounds as a prelude to presenting their use as umpolung reagents, to promote the selective coupling of two nucleophilic species <italic>via</italic> 2e<sup>−</sup> oxidation.
Topics & Concepts
NucleophileReagentIodineCoupling (piping)ChemistryCombinatorial chemistryOrganic chemistryMaterials scienceCatalysisComposite materialOxidative Organic Chemistry ReactionsAsymmetric Synthesis and CatalysisFluorine in Organic Chemistry