Obesity accelerates immune evasion of non-small cell lung carcinoma via TFEB-dependent upregulation of Siglec-15 and glycolytic reprogramming
Cai Zhang, Lijie Zhou, Songyang Li, Junwei Zhao, Xianchun Meng, Liwei Ma, Yongfeng Wang, Cai Li, Lu Zheng, Liang Ming
Topics & Concepts
TFEBTumor microenvironmentCancer researchDownregulation and upregulationImmune systemCytotoxic T cellBiologyLung cancerImmunotherapyImmunologyImmune checkpointMedicineInternal medicineAutophagyApoptosisGeneIn vitroBiochemistryCancer Immunotherapy and BiomarkersImmune cells in cancerCancer Cells and Metastasis