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The novel small molecule BH3 mimetic nobiletin synergizes with vorinostat to induce apoptosis and autophagy in small cell lung cancer

Yuqian Li, Fang Fan, Yuan-ru Wang, Luyao Li, Yajun Cao, Simeng Gu, Shuai-shuai Liu, Yue Zhang, Jie Wang, Lu Tie, Yan Pan, Huifang Li, Xuejun Li, Huifang Li, Huifang Li, Xuejun Li

2023Biochemical Pharmacology14 citationsDOI

Topics & Concepts

VorinostatNobiletinAutophagyChemistryApoptosisCancer researchProgrammed cell deathPI3K/AKT/mTOR pathwayIn vivoProtein kinase BPharmacologyCell biologyBiologyHistone deacetylaseBiochemistryHistoneAntioxidantGeneFlavonoidBiotechnologyCancer Mechanisms and TherapyPeptidase Inhibition and AnalysisLung Cancer Research Studies
The novel small molecule BH3 mimetic nobiletin synergizes with vorinostat to induce apoptosis and autophagy in small cell lung cancer | Litcius