C1q/tumor necrosis factor-related protein-1 attenuates microglia autophagy and inflammatory response by regulating the Akt/mTOR pathway

Huilin Wang, Qinghui Liu, Xiaojie Zhang

2020Life Sciences33 citationsDOI

Topics & Concepts

AutophagyPI3K/AKT/mTOR pathwayMicrogliaTumor necrosis factor alphaProtein kinase BCancer researchInflammatory responseTumor necrosis factor αInflammationRPTORCell biologyMedicineSignal transductionChemistryImmunologyApoptosisBiologyBiochemistryAdipokines, Inflammation, and Metabolic DiseasesAutophagy in Disease and TherapyNeuroinflammation and Neurodegeneration Mechanisms