Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties
Wen Shi, Yunfan Kong, Yajuan Su, Mitchell Kuss, Xiping Jiang, Xiaowei Li, Jingwei Xie, Bin Duan
Abstract
. In addition, the dynamic hydrogels showed the anti-oxidative properties of high free radical and ROS scavenging capacity, which was verified by the DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radical assay and ROS fluorescence staining. Overall, this novel class of cytocompatible, self-healing, dual stimuli responsive, antibacterial, anti-oxidative, and injectable hydrogels could be promising as a wound dressing for chronic wound healing.
Topics & Concepts
Self-healing hydrogelsTannic acidGenipinHyaluronic acidChemistryAntibacterial activityReactive oxygen speciesCovalent bondPolyphenolWound healingDPPHGlutaraldehydeAntioxidantOrganic chemistryBiochemistryChitosanImmunologyBacteriaBiologyGeneticsWound Healing and TreatmentsAntimicrobial agents and applicationsHydrogels: synthesis, properties, applications