Ultrasound-promoted solvent-free synthesis of some new <i>α</i> -aminophosphonates as potential antioxidants
Meson Haji Basha, Chennamasetty Subramanyam, K. Prasada Rao
Abstract
Abstract Ultrasonic irradiation has been adopted in order to achieve an efficient synthesis of some novel α- aminophosphonates by Pudovik reaction. Major benefits of this method are as follows: eco-friendly, free of catalyst, high yielding, uncomplicated work-up procedure, short reaction time, and solvent free condition. Spectral characterisation and elemental analysis of the synthesized samples was carried out. In vitro antioxidant activity of the title compounds was screened by DPPH˙, O 2- ˙ and NO˙ scavenging methods. Good activity was shown by most of the compounds as compared with the standards.
Topics & Concepts
ChemistryDPPHCatalysisAntioxidantSolventEnvironmentally friendlyGreen chemistryOrganic chemistryUltrasoundScavengingElemental analysisNuclear chemistryCombinatorial chemistryReaction mechanismAcousticsBiologyPhysicsEcologyOrganophosphorus compounds synthesisSynthesis and Reactivity of Sulfur-Containing CompoundsSynthesis and Characterization of Heterocyclic Compounds