Capsid Structure of <i>Leishmania</i> RNA Virus 1
Michaela Procházková, Tibor Füzik, Danyil Grybchuk, Francesco Luca Falginella, Lucie Podešvová, Vyacheslav Yurchenko, Robert Vácha, Pavel Plevka
Abstract
cells. The structure of the LRV1 capsid enables the rational design of compounds targeting the putative mRNA cleavage site. Such inhibitors may be used as treatments for mucocutaneous leishmaniasis.
Topics & Concepts
CapsidBiologyVirologyLeishmaniaRNALeishmaniasisVirusGeneticsGeneParasite hostingComputer scienceWorld Wide WebResearch on Leishmaniasis StudiesViral Infections and VectorsTrypanosoma species research and implications