Selective Viramidine-Loaded Aptamer-Nanoparticles Trigger Cell Cycle Arrest in Nucleolin-Expressed Hepatoma Cells Through Modulation of CDC25A/p53/PI3k Pathway
Ahmed Abdrabou, Hanaa H. Ahmed, Mohamed S. Kishta, Khairy M. A. Zoheir
Topics & Concepts
NucleolinCDC25ADownregulation and upregulationChemistryCell cycleAptamerCancer cellPI3K/AKT/mTOR pathwayCancer researchCell biologyCellCell cycle checkpointMolecular biologyApoptosisCytoplasmCancerBiologyBiochemistryMedicineInternal medicineGeneNucleolusRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesNanoparticle-Based Drug Delivery