Case Report: Cutaneous Leishmaniasis due to Leishmania (Viannia) panamensis in Two Travelers Successfully Treated with Miltefosine
Sarah Mann, Tanit Phupitakphol, Brian Davis, Sabrina Newman, José Antonio Suárez, Andrés F. Henao‐Martínez, Carlos Franco‐Paredes
Abstract
We present two cases of Leishmania (V) panamensis in returning travelers from Central America successfully treated with miltefosine. The couple presented with ulcerative skin lesions nonresponsive to antibiotics. Skin biopsy with polymerase chain reaction (PCR) revealed L. (V) panamensis. To prevent the development of mucosal disease and avoid the inconvenience of parental therapy, we treated both patients with oral miltefosine. We suggest that miltefosine represents an important therapeutic alternative in the treatment of cutaneous lesions caused by L. panamensis and in preventing mucosal involvement.
Topics & Concepts
MiltefosineCutaneous leishmaniasisLeishmaniaLeishmaniasisDermatologyAntibioticsSkin biopsyBiologyMedicineBiopsyMicrobiologyImmunologyPathologyParasite hostingVisceral leishmaniasisWorld Wide WebComputer scienceResearch on Leishmaniasis StudiesTrypanosoma species research and implications