HBV Reactivation in Immunosuppressed Patients: Screening, Prevention, and Management Including Solid Organ Transplant Recipients
Philip Vutien, Mindie H. Nguyen
Abstract
Hepatitis B virus (HBV) infection remains a global health challenge, affecting over 254 million individuals chronically and contributing significantly to cirrhosis, liver failure, and hepatocellular carcinoma. Despite advancements in antiviral therapy, HBV reactivation remains a critical concern, particularly in immunosuppressed individuals, including non-transplant patients undergoing immunosuppressive therapy and solid organ transplant recipients. This review provides screening and management strategies for HBV reactivation in these populations.
Topics & Concepts
MedicineHepatocellular carcinomaHepatitis B virusSolid organCirrhosisImmunosuppressionOrgan transplantationAntiviral therapyHepatitis BImmunologyIntensive care medicineInternal medicineTransplantationVirusChronic hepatitisHepatitis B Virus StudiesHepatitis C virus researchLiver Disease Diagnosis and Treatment