Impaired BCAA catabolism in adipose tissues promotes age-associated metabolic derangement
Hyesook Han, Eunyong Ahn, Eun Seo Park, Tom Huh, Seri Choi, Yongmin Kwon, Byeong Hun Choi, Jueun Lee, Yoon Ha Choi, Yu‐Jin Jeong, Gwang Bin Lee, Minji Kim, Je Kyung Seong, Hyun Mu Shin, Hang‐Rae Kim, Myeong Hee Moon, Jong Kim, Geum‐Sook Hwang, Seung‐Hoi Koo
Topics & Concepts
CatabolismAdipose tissuemTORC1EndocrinologyInternal medicineBiologySenescenceAdipocyteWhite adipose tissueAdipogenesisGlucose homeostasisCell biologyMetabolismMedicineSignal transductionDiabetes mellitusInsulin resistancePI3K/AKT/mTOR pathwayAdipose Tissue and MetabolismSingle-cell and spatial transcriptomicsAdipokines, Inflammation, and Metabolic Diseases