Litcius/Paper detail

Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors

Khaled El‐Adl, Abdel‐Ghany A. El‐Helby, Helmy Sakr, Alaa Elwan

2020Bioorganic Chemistry78 citationsDOI

Topics & Concepts

ChemistryTopoisomeraseQuinoxalineIntercalation (chemistry)DNAStereochemistryDocking (animal)Covalent bondIC50Small moleculeEnzymeMolecular modelCombinatorial chemistryIn vitroBiochemistryOrganic chemistryNursingMedicineSynthesis and Biological EvaluationCancer therapeutics and mechanismsSynthesis and biological activity
Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors | Litcius