Evaluation of Lanthanide-Doped Upconverting Nanoparticles for <i>in Vitro</i> and <i>in Vivo</i> Applications
Dana M. Samhadaneh, Gabrielle A. Mandl, Zhao Han, Maryam Mahjoob, Stephanie C. Weber, Marius Tuznik, David A. Rudko, John A. Capobianco, Ursula Stochaj
Abstract
contrast agents; they clearly outperformed the clinically used Gadovist. Taken together, our interdisciplinary work provides robust evidence for the nontoxicity of Ln-UCNPs. This sets the stage for the translation of Ln-UCNP for use in complex biological systems.
Topics & Concepts
In vivoBiophysicsIn vitroChemistryHeLaCell biologyNanotechnologyBiologyBiochemistryMaterials scienceBiotechnologyNanoplatforms for cancer theranosticsbioluminescence and chemiluminescence researchUltrasound and Hyperthermia Applications