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Synthesis and mitochondria-localized iridium (III) complexes induce cell death through pyroptosis and ferroptosis pathways

Huiyan Hu, Fan Zhang, Z. Sheng, Shuang Tian, Gechang Li, Shuanghui Tang, Yajie Niu, Jiawan Yang, Yunjun Liu

2024European Journal of Medicinal Chemistry25 citationsDOI

Topics & Concepts

ChemistryPyroptosisProgrammed cell deathIridiumMitochondrionApoptosisCell biologyAutophagyCellBiochemistryCatalysisBiologyFerroptosis and cancer prognosisinterferon and immune responsesInflammasome and immune disorders
Synthesis and mitochondria-localized iridium (III) complexes induce cell death through pyroptosis and ferroptosis pathways | Litcius