Current Update on Biomarkers for Detection of Cancer: Comprehensive Analysis
Ankur Kaushal, Narinder Kaur, Surbhi Sharma, Anil Kumar Sharma, Deepak Kala, Hridayesh Prakash, Shagun Gupta
Abstract
Early and effective diagnosis of cancer is decisive for its proper management. In this context biomarker-based cancer diagnosis is budding as one of the promising ways for early detection, disease progression monitoring, and effective cancer therapy. Integration of Biosensing devices with different metallic/nonmetallic nanoparticles offers amplification and multiplexing capabilities for simultaneous detection of cancer biomarkers (CB's). This study provides a comprehensive analysis of the most recent designs and fabrication methodologies designed for developing electrochemical biosensors (EB) for early detection of cancers. The role of biomarkers in cancer therapeutics is also discussed.