A medicinal chemist who reshaped the antiviral drug industry: John Charles Martin (1951–2021)
Guangdi Li, Erik De Clercq
Abstract
John Charles Martin should be remembered as a visionary medicinal chemist who was involved in the coinvention, development, or management of many FDA-approved antiviral drugs such as ganciclovir, stavudine, didanosine, cidofovir, oseltamivir, adefovir dipivoxil, tenofovir disoproxil fumarate, tenofovir alafenamide, sofosbuvir, and remdesivir.
Topics & Concepts
DidanosineAdefovirVirologyTenofovirChemistCidofovirLamivudinePharmacologyStavudineMedicineZidovudineHuman immunodeficiency virus (HIV)ChemistryVirusViral diseaseHepatitis B virusOrganic chemistryHepatitis C virus researchHIV/AIDS drug development and treatmentHepatitis B Virus Studies