A benzothiazolium-based fluorescent probe with ideal p<i>K</i><sub>a</sub> for mitochondrial pH imaging and cancer cell differentiation
Bo Lin, Li Fan, Ying Zhou, Jinyin Ge, Xueli Wang, Chuan Dong, Shaomin Shuang, Man Shing Wong
Abstract
A benzothiazolium-based fluorescent pH probe <bold>HTBT2</bold> with an ideal p<italic>K</italic><sub>a</sub> of 8.04 ± 0.02 for imaging mitochondrial pH in living cells.
Topics & Concepts
FluorescenceIdeal (ethics)BiophysicsChemistryMaterials scienceNanotechnologyOpticsPhysicsBiologyEpistemologyPhilosophyMolecular Sensors and Ion DetectionMetal-Organic Frameworks: Synthesis and ApplicationsElectron Spin Resonance Studies