Management of Locally Advanced Esophageal Cancer
Binay Thakur, Mukti Devkota, Manish Chaudhary
Abstract
Esophageal cancer is diagnosed usually at a locally advanced stage. Surgery alone has less optimal results and a multimodality approach has been established as the standard of care for cII-III stages of esophageal cancer. This review focuses on the recent evidences of management of esophageal cancer with various variations in approaches in Eastern and Western countries. The major difference is the selection of induction treatment. Till the results of some ongoing trials become available, most of the evidences support neoadjuvant chemoradiation followed by surgery for squamous cell carcinoma and perioperative chemotherapy and surgery for adenocarcinoma.
Topics & Concepts
MedicineEsophageal cancerPerioperativeChemotherapyCancerStage (stratigraphy)Neoadjuvant therapyAdenocarcinomaGeneral surgeryEsophageal adenocarcinomaOncologySurgeryInternal medicineBiologyBreast cancerPaleontologyEsophageal Cancer Research and TreatmentGastric Cancer Management and OutcomesEsophageal and GI Pathology