Screening in serum-derived medium reveals differential response to compounds targeting metabolism
Keene L. Abbott, Ahmed Ali, Dominick Casalena, T. Brian, Raphaël Ferreira, Jaime H. Cheah, Christian K. Soule, Amy Deik, Tenzin Kunchok, Daniel R. Schmidt, Steffen Renner, Sophie Honeder, Michelle Xiao Wu, Sze Ham Chan, Tenzin Tseyang, Andrew T. Stoltzfus, Sarah L. J. Michel, Daniel Greaves, Peggy P. Hsu, Christopher Ng, Chelsea J. Zhang, Ali Farsidjani, Johnathan R. Kent, Maria Lucia L. Madariaga, Iva Monique T. Gramatikov, Nicholas J. Matheson, Caroline A. Lewis, Clary B. Clish, Matthew G. Rees, Jennifer A. Roth, Lesley A. Mathews Griner, Alexander Muir, Douglas S. Auld, Matthew G. Vander Heiden
Topics & Concepts
Cell cultureHigh-throughput screeningSmall moleculeNutrientCellMetabolismDrug discoveryCellular metabolismDrugCell growthBiologyCancer cellIn vitroPharmacologyComputational biologyCancer researchCell biologyBiochemistryCancerGeneticsEcologyCancer, Hypoxia, and MetabolismMicrobial Metabolic Engineering and BioproductionBioinformatics and Genomic Networks