Day-to-day variation of the kidney proximal tubular injury markers urinary cystatin C, KIM1, and NGAL in patients with chronic kidney disease
Inga Soveri, Johanna Helmersson‐Karlqvist, Bengt Fellström, Anders Larsson
Abstract
percentiles of the CV values as a limit for clinical change means that NGAL has to change by 83.3%, KIM1 by 45.5% and Cystatin C by 46.3% before the change can be considered clinically significant in patients with chronic kidney disease.
Topics & Concepts
MedicineCreatinineCystatin CKidney diseaseNephrologyRenal functionInternal medicineUrologyUrinary systemUrinePercentileCoefficient of variationCystatinMorningBiomarkerGastroenterologyEndocrinologyBiologyChemistryStatisticsBiochemistryChromatographyMathematicsChronic Kidney Disease and DiabetesAcute Kidney Injury ResearchDialysis and Renal Disease Management