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Human bone mesenchymal stem cells-derived exosomal miRNA-361-5p alleviates osteoarthritis by downregulating DDX20 and inactivating the NF-κB signaling pathway

Yunxia Tao, Jing Zhou, Zhen Wang, Huaqiang Tao, Jiaxiang Bai, Gaoran Ge, Wenming Li, Wei Zhang, Yuefeng Hao, Xing Yang, Dechun Geng

2021Bioorganic Chemistry86 citationsDOI

Topics & Concepts

ChemistryDownregulation and upregulationMesenchymal stem cellmicroRNAChondrocyteCell biologyMicrovesiclesNF-κBWestern blotSignal transductionCartilageMolecular biologyCancer researchBiologyIn vitroBiochemistryAnatomyGeneOsteoarthritis Treatment and MechanismsExtracellular vesicles in diseaseMicroRNA in disease regulation
Human bone mesenchymal stem cells-derived exosomal miRNA-361-5p alleviates osteoarthritis by downregulating DDX20 and inactivating the NF-κB signaling pathway | Litcius