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Doctor—Should I get the <scp>COVID</scp>‐19 vaccine? Infection and immunization in individuals with neuromuscular disorders

Sasha Živković, Gregory Gruener, Pushpa Narayanaswami

2021Muscle & Nerve28 citationsDOIOpen Access PDF

Abstract

The clinical course of neuromuscular disorders (NMDs) can be affected by infections, both in immunocompetent individuals, and in those with reduced immunocompetence due to immunosuppressive/immunomodulating therapies. Infections and immunizations may also trigger NMDs. There is a potential for reduced efficacy of immunizations in patients with reduced immunocompetence. The recent vaccination program for coronavirus disease-2019 (COVID-19) raises several questions regarding the safety and efficacy of this vaccine in individuals with NMDs. In this Practice Topic article, we address the role of vaccine-preventable infections in NMDs and the safety and efficacy of immunization in individuals with NMDs, with emphasis on vaccination against COVID-19.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)ImmunizationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakMedicineVirologyImmunologyAntibodyInternal medicineOutbreakDiseaseInfectious disease (medical specialty)Peripheral Neuropathies and DisordersLong-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research
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