Litcius/Paper detail

Structure of the nutrient-sensing hub GATOR2

Max L. Valenstein, Kacper B. Rogala, Pranav V. Lalgudi, Edward J. Brignole, Xin Gu, Robert A. Saxton, Lynne Chantranupong, Jonas Kolibius, Jan-Philipp Quast, David M. Sabatini

2022Nature79 citationsDOIOpen Access PDF

Topics & Concepts

mTORC1Cell biologyScaffold proteinBiologyNutrient sensingProtein subunitAmino acidBiophysicsChemistryBiochemistrySignal transductionPI3K/AKT/mTOR pathwayGeneRNA and protein synthesis mechanismsAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic Engineering