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Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4

Benjamin Rein, Tao Tan, Fengwei Yang, Wei Wang, Jamal B. Williams, Freddy Zhang, Alea A. Mills, Zhen Yan

2020Molecular Psychiatry63 citationsDOIOpen Access PDF

Topics & Concepts

NeuroscienceGABAergicPrefrontal cortexAutismAutism spectrum disorderNeurotransmissionPsychologyBiologyInhibitory postsynaptic potentialCognitionGeneticsPsychiatryReceptorCongenital heart defects researchGenomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders
Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4 | Litcius