Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies
Kátia de Paiva Lopes, Gijsje J. L. Snijders, Jack Humphrey, Amanda Allan, Marjolein A. M. Sneeboer, Elisa Navarro, Brian M. Schilder, Ricardo A. Vialle, Madison Parks, Roy Missall, Welmoed van Zuiden, Frederieke Gigase, Raphael Kübler, Amber Berdenis van Berlekom, Emily M. Hicks, Chotima Böttcher, Josef Priller, René S. Kahn, Lot D. de Witte, Towfique Raj
Topics & Concepts
TranscriptomeBiologyMicrogliaQuantitative trait locusAlternative splicingExpression quantitative trait lociHuman brainCandidate geneDiseaseLocus (genetics)GeneticsNeuroscienceGeneGene expressionSingle-nucleotide polymorphismPathologyGenotypeMedicineImmunologyExonInflammationNeuroinflammation and Neurodegeneration MechanismsPeroxisome Proliferator-Activated ReceptorsAlzheimer's disease research and treatments