Additive-free, <i>N</i> -chlorosuccinimide-promoted electrophilic phosphorothiolation/cyclization of alkynes with P(O)SH compounds to access heterocyclic phosphorothiolated molecules
Pengbo Zhang, Weilong Qu, Shuai Yang, Longyu Wang, Linxiu Zhang, Xianglong Zhu, Xia Gao
Abstract
A N -chlorosuccinimide-promoted electrophilic phosphorothiolation/cyclization of alkynes for the construction of phosphorothiolated heterocycles under metal- and additive-free conditions has been developed.
Topics & Concepts
ChemistryElectrophileMoleculeMedicinal chemistryElectrophilic additionCombinatorial chemistryOrganic chemistryCatalysisSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods