Development and evaluation of polymeric micelle containing tablet formulation for poorly water-soluble drug: tamoxifen citrate
Kıvılcım Öztürk-Atar, Meryem Kaplan, Sema Çalış
Abstract
TEVA). It can be reasonably expected that the obtained drug dissolution rate and increased cytotoxicity to tumor cells will result in an increase of TMX bioavailability and tolerability associated with an important dose reduction and decreased side effects.
Topics & Concepts
MicelleEthylene glycolChemistryBioavailabilitySolubilityDissolutionPEG ratioBiocompatibilityDissolution testingAqueous solutionChromatographyNuclear chemistryPharmacologyOrganic chemistryBiopharmaceutics Classification SystemMedicineFinanceEconomicsNanoparticle-Based Drug DeliveryDrug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems