Optimizing Treatment for Carbapenem-Resistant <i>Acinetobacter baumannii</i> Complex Infections: A Review of Current Evidence
Seong Jin Choi, Eu Suk Kim
Abstract
complex, is being reassessed. High-dose ampicillin-sulbactam-based combination therapies, as well as combinations of sulbactam and durlobactam, which prevent the hydrolysis of sulbactam and binds to penicillin-binding protein 2, have shown promising results. This review introduces recent advancements in CRAB infection treatment based on clinical trial data, highlighting the need for optimized treatment protocols and comprehensive clinical trials to combat the evolving threat of CRAB effectively.
Topics & Concepts
Acinetobacter baumanniiAcinetobacterMicrobiologyMedicineCarbapenemIntensive care medicineBiologyPseudomonas aeruginosaAntibioticsBacteriaGeneticsAntibiotic Resistance in BacteriaVibrio bacteria research studiesAntibiotic Use and Resistance