Litcius/Paper detail

Downregulation of lncRNA TSLNC8 promotes melanoma resistance to BRAF inhibitor PLX4720 through binding with PP1α to re-activate MAPK signaling

Yongzhi Han, Jing Fang, Zhiwei Xiao, Jian Deng, Minghui Zhang, Lixiong Gu

2021Journal of Cancer Research and Clinical Oncology23 citationsDOIOpen Access PDF

Topics & Concepts

MelanomaDownregulation and upregulationCancer researchMAPK/ERK pathwayBiologyVemurafenibMEK inhibitorKinaseCell biologyBiochemistryMetastatic melanomaGeneMelanoma and MAPK PathwaysCancer-related molecular mechanisms researchCancer Mechanisms and Therapy
Downregulation of lncRNA TSLNC8 promotes melanoma resistance to BRAF inhibitor PLX4720 through binding with PP1α to re-activate MAPK signaling | Litcius