<i>In situ</i>detection of miRNA-21 in MCF-7 cell-derived extracellular vesicles using the red blood cell membrane vesicle strategy
Di Wu, Wenyue Zhang, Tao Li, Fen Li, Qingfang Feng, Xiao Cheng, Yingshu Guo
Abstract
We propose an innovative strategy of membrane fusion between red blood cell membrane vesicles (RVs) and extracellular vesicles (EVs) to deliver fluorescence detection probes without damaging the membrane vesicle structure of EVs.
Topics & Concepts
VesicleMembraneIn situMicrovesiclesChemistryExtracellular vesiclesCellExtracellularRed blood cellBiophysicsCell membraneExtracellular vesiclemicroRNACell biologyBiochemistryBiologyGeneOrganic chemistryExtracellular vesicles in diseaseMicroRNA in disease regulationAdvanced biosensing and bioanalysis techniques