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Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

Yan Huang, Biao Hu, Ya Liu, Ling‐Qi Xie, Yu Dai, Yu-Ze An, Xinyi Peng, Yalun Cheng, Yi‐Fan Guo, Weihong Kuang, Yao Xiao, Xin Chen, Yongjun Zheng, Guiyang Xie, Jianping Wang, Hui Peng, Xiang-Hang Luo

2025Cell Metabolism12 citationsDOI

Topics & Concepts

Hippocampal formationMitochondrionHippocampusCognitive declineNeuroscienceCognitionSynapseBiologySynaptic vesicleSecretionEndogenyMechanism (biology)EndocrinologyCell biologyEffects of sleep deprivation on cognitive performanceOxidative stressMedicineInternal medicineNeurotransmissionPhysical exercisePsychologyMitochondrial DNAEnergy metabolismOxidative phosphorylationinterferon and immune responsesCellular transport and secretionMitochondrial Function and Pathology
Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender | Litcius