E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2
Jie Zhang, Lei Cao, Amy Gao, Ruiqing Ren, Liwen Yu, Qian Li, Yapeng Liu, Wenqian Qi, Yonghao Hou, Wenhai Sui, Guohai Su, Yun Zhang, Cheng Zhang, Meng Zhang
Topics & Concepts
Innate immune systemTLR4Ubiquitin ligaseCell biologySignal transductionBiologyToll-like receptorUbiquitinImmune systemImmunologyBiochemistryGeneNF-κB Signaling PathwaysUbiquitin and proteasome pathwaysImmune Response and Inflammation