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N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis

Wan-Li Duan, Yaping Ma, Xuejie Wang, Changsheng Ma, Bo Han, Zhi-Mei Sheng, Hao Dong, Liying Zhang, P. Andy Li, Baogang Zhang, Maotao He

2024European Journal of Pharmacology22 citationsDOI

Topics & Concepts

IschemiaPharmacologyProgrammed cell deathReperfusion injuryMedicineAutophagyApoptosisPopulationBiologyInternal medicineBiochemistryEnvironmental healthFerroptosis and cancer prognosisCancer-related molecular mechanisms researchMicroRNA in disease regulation
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis | Litcius