ERK/HIF-1α/VEGF pathway: a molecular target of ELABELA (ELA) peptide for attenuating cardiac ischemia–reperfusion injury in rats by promoting angiogenesis
Kamran Rakhshan, Masoomeh Sharifi, Fatemeh Ramezani, Yaser Azizi, Nahid Aboutaleb
Topics & Concepts
AngiogenesisMyocardial fibrosisMedicineMasson's trichrome stainWestern blotCardiac fibrosisLigationFibrosisMAPK/ERK pathwayImmunohistochemistryIschemiaReperfusion injuryVascular endothelial growth factorInternal medicinep38 mitogen-activated protein kinasesCardiologyEndocrinologyVEGF receptorsChemistrySignal transductionBiochemistryGeneApelin-related biomedical researchCardiovascular, Neuropeptides, and Oxidative Stress ResearchNuclear Receptors and Signaling