The E3 ubiquitin ligase Itch limits the progression of post-traumatic osteoarthritis in mice by inhibiting macrophage polarization
Xi Lin, Weijian Wang, Andrew McDavid, Hao Xu, Brendan F. Boyce, Lianping Xing
Topics & Concepts
InflammationMedicineMacrophage polarizationOsteoarthritisImmunologyUbiquitin ligaseProinflammatory cytokineUbiquitinMacrophageCancer researchPathologyBiologyBiochemistryIn vitroAlternative medicineGeneOsteoarthritis Treatment and MechanismsBone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research