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Transition Metal‐Free Aromatic C−H, C−N, C−S and C−O Borylation

Lu Luo, Shuai Tang, Jiangyue Wu, Shiwei Jin, Hua Zhang

2023The Chemical Record18 citationsDOI

Abstract

Aromatic organoboron compounds are highly valuable building blocks in organic chemistry. They were mainly synthesized through aromatic C-H and C-Het borylation, in which transition metal-catalysis dominate. In the past decade, with increasing attention to sustainable chemistry, numerous transition metal-free C-H and C-Het borylation transformations have been developed and emerged as efficient methods towards the synthesis of aromatic organoboron compounds. This account mainly focuses on recent advances in transition metal-free aromatic C-H, C-N, C-S, and C-O borylation transformations and provides insights to where further developments are required.

Topics & Concepts

BorylationOrganoboron compoundsTransition metalChemistryCatalysisOrganic chemistryAlkylArylOrganoboron and organosilicon chemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions
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