Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
Harmandeep Kaur Gulati, Sushil Choudhary, Nitish Kumar, Ajaz Ahmed, Kavita Bhagat, Jatinder Singh, Atamjit Singh, Ajay Kumar, Preet Mohinder Singh Bedi, Harbinder Singh, Debaraj Mukherjee
Topics & Concepts
TacrineChemistryAcetylcholinesteraseTriazoleGlycoconjugateCholinesteraseStereochemistryEnzymePharmacologyBiochemistryOrganic chemistryMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsClick Chemistry and Applications