Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis
Mohmad Alsabani, Simon T. Abrams, Zhenxing Cheng, Ben Morton, Steven Lane, Samar Alosaimi, Weiping Yu, Guozheng Wang, Cheng‐Hock Toh
Topics & Concepts
SepsisNeutrophil extracellular trapsInflammationSystemic inflammationMedicineImmunologySeptic shockCytokineEx vivoInternal medicinePharmacologyBiologyIn vivoBiotechnologyNeutrophil, Myeloperoxidase and Oxidative MechanismsCell Adhesion Molecules ResearchImmune cells in cancer