Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon re-infection
Adrian Straub, Simon Grassmann, Sebastian Jarosch, Lena Richter, Philipp Hilgendorf, Monika Hammel, K Wagner, Veit R. Buchholz, Kilian Schober, Dirk H. Busch
Topics & Concepts
BiologyAvidityEpitopeT-cell receptorPolyclonal antibodiesT cellImmune systemCD8PathogenAntigenImmunologyVirologyCAR-T cell therapy researchT-cell and B-cell ImmunologyImmune Cell Function and Interaction