Palladium-Catalyzed One-Pot Synthesis of Pyrroloindolines from 2-Alkynyl Arylazides and Thioacetamides
Ping Li, Fan Yang, Guiwen Hu, Xiaoxiang Zhang
Abstract
A novel and efficient synthetic method for the preparation of various pyrroloindolines from 2-alkynyl arylazides and thioacetamides was developed. The reaction was carried out in a one-pot process under mild reaction conditions to afford the products in moderate to good yields, which has the potential to be used in organic synthesis.
Topics & Concepts
ChemistryPalladiumCatalysisOne-pot synthesisReaction conditionsCombinatorial chemistryOrganic chemistryOrganic synthesisCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsSynthesis and Characterization of Pyrroles