Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water
Henian Peng, Yuying Li, Duanshuai Tian, He Yang, Guangqing Xu, Wenjun Tang
Abstract
A series of unsaturated carbonyls, quinones, and pyridinium salts have been effectively reduced to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields with tetrahydroxydiboron/water as a mild, convenient, and metal-free reduction system. Deuterium-labeling experiments have revealed this protocol to be an exclusive transfer hydrogenation process from water.
Topics & Concepts
ChemistryPyridiniumMetalMetal carbonylDeuteriumOrganic chemistryInorganic chemistryQuantum mechanicsPhysicsOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisChemical Synthesis and Analysis