Synthesis and modification of ZIF-8 and its application in drug delivery and tumor therapy
Qiuxiang Wang, Yue Sun, Shangfei Li, Pingping Zhang, Qingqiang Yao
Abstract
has been extensively studied in the medical field due to its low toxicity and good biocompatibility. This review introduces the preparation and functional modification of ZIF-8, and its application in drug delivery, focusing on the single-stimulus and multi-stimulus response release of drugs in ZIF-8 materials, the integrated role of diagnosis and treatment with ZIF-8 in cancer treatment, and its application in the synergistic therapy of multiple cancer treatment methods. We summarize the latest developments of ZIF-8 in the field of drug delivery and tumor therapy, and present the main challenges that remain to be resolved in the ZIF-8 drug delivery system.
Topics & Concepts
Drug deliveryBiocompatibilityCancer therapyDrugNanotechnologyMaterials scienceMedicinePharmacologyCancerInternal medicineMetallurgyMetal-Organic Frameworks: Synthesis and ApplicationsNanoplatforms for cancer theranosticsBoron Compounds in Chemistry