A rapid, simple, high-performance liquid chromatography method for the clinical measurement of beta-lactam antibiotics in serum and interstitial fluid
Alaa Riezk, Richard Wilson, Timothy M. Rawson, Vasin Vasikasin, P. van Arkel, Trevor J. Ferris, L. D. Haigh, Anthony E. G. Cass, Alison Holmes
Abstract
: the developed method is simple, rapid, accurate and clinically applicable for the quantification of three penicillin classes.
Topics & Concepts
AntibioticsChromatographyBeta-lactamLactamChemistryInterstitial fluidMedicineStereochemistryInternal medicineBiochemistryAntibiotics Pharmacokinetics and EfficacyPneumonia and Respiratory InfectionsAntibiotic Resistance in Bacteria