Translating the Microbiome: What’s the Target?
Paul W. O’Toole, Tarini Shankar Ghosh, Sourav Goswami, Paolo Manghi, Nicola Segata, Fergus Shanahan
Abstract
Two celebrated scientific movements, precision medicine and microbiome science, promise to converge on clinical medicine. Both are relevant to a diversity of clinical disciplines and capture the attention of increasingly expectant patients seeking individualized treatments based on exquisitely precise diagnostics. Clinicians responding to requests for a microbiome test often have no understanding of how such a test might be interpreted. Other than known infectious agents, what can a doctor find in a single isolated fecal microbiome analysis that is therapeutically actionable?
Topics & Concepts
MicrobiomeHuman microbiomeHuman Microbiome ProjectMedicineDiseaseIntestinal MicrobiomePrecision medicineBioinformaticsBiologyPathologyGut microbiota and healthClostridium difficile and Clostridium perfringens researchHelicobacter pylori-related gastroenterology studies