Cholesterol May be a Negative Whereas Triglycerides Positive Acute Phase Reactants in the Plasma
Mehmet Rami Helvacı, Semih Salaz, Atilla Yalçın, Orhan Ekrem Muftuoglu, Abdulrazak Abyad, Lesley Pocock
Abstract
INTRODUCTONT he endothelium is a monolayer of endothelial cells which constitutes the inner cellular lining of arteries, veins, capillaries, and lymphatics.It is the major player in the control of blood fluidity, platelets (PLT) aggregation, and vascular tone.It may be the major actor in immunology, inflammation, and angiogenesis.It may also be important in endocrinology.The endothelial cells control vascular tone and blood flow by synthesizing and releasing nitric oxide, metabolites of arachidonic acid, and reactive oxygen species.In addition, they are also important for generation of vasoactive hormones such as angiotensin II.An endothelial dysfunction linked to an imbalance in the synthesis and/or release of these endothelial factors may explain the initiation of several cardiovascular pathologies including hypertension (HT) and atherosclerosis.On the other hand, chronic endothelial damage may be the major underlying cause of aging and death by causing disseminated atherosclerosis and end-organ failures in human being. [1,2]uch higher blood pressure (BP) of the afferent vasculature may be the major underlying factor by causing recurrent injuries on vascular endothelium.Probably, whole afferent vasculature including capillaries is mainly involved in